mycosporine-like amino acid biosynthetic genes from a halotolerant cyanobacterium
نویسندگان
چکیده
Identification and up-regulation of biosynthetic genes required for accumulation of 1 mycosporine-2-glycine under salt stress in halotolerant cyanobacterium Aphanothece 2 halophytica 3 4 Rungaroon Waditee-Sirisattha, Hakuto Kageyama, Warangkana Sopun, Yoshito 5 Tanaka, Teruhiro Takabe 6 7 Research Institute of Meijo University, Nagoya 468-8502, Japan; Department of 8 Microbiology, Faculty of Science, Chulalongkorn University, Patumwan, Bangkok 10330, 9 Thailand; Graduate School of Environmental and Human Sciences, Meijo University, 10 Nagoya 468-8502, Japan 11 12 13 Running title: MAA in halotolerant cyanobacterium 14 15 16 To whom correspondence should be addressed: Teruhiro Takabe, Research Institute, Meijo 17 University, Nagoya 468-8502, Japan, Tel: 81-52-838-2277; Fax: 81-52-832-1545; 18 E-mail: [email protected] 19 20 21 22 Abbreviations: AAligase, D-ala-D-ala ligase, A. halophytica, Aphanothece halophytica; 23 CNligase, ligation of glycine to 4-DG; DDG, demethyl 4-deoxygadusol; 4-DG, 424 deoxygadusol; MAA, Mycosporine and mycosporine-like amino acids; O-MT, O25 methyltransferase; NRPS, nonribosomal peptide synthetase. 26 27
منابع مشابه
Nitrate and amino acid availability affects glycine betaine and mycosporine-2-glycine in response to changes of salinity in a halotolerant cyanobacterium Aphanothece halophytica.
A halotolerant cyanobacterium Aphanothece halophytica thrives in extreme salinity with accumulation of a potent osmoprotectant glycine betaine. Recently, this cyanobacterium was shown to accumulate sunscreen molecule mycosporine-2-glycine significantly at high salinity. In this study, we investigated effects of nitrate and amino acid provision on the accumulation of glycine betaine and mycospor...
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